Even before the current pandemic, the nurse leader (NL) role was demanding of time, energy, and resources. These demands often cause stress, fatigue, and burnout. The focused-on outcome metrics, increased regulations, and economic downturn are challenges that NLs have continued to face. This study, undertaken before the pandemic, provides understanding of the professional quality of life and work engagement among NLs. Findings revealed that experienced NLs with doctorates have higher levels of compassion satisfaction and engagement, and have lowest levels of burnout and secondary traumatic stress.